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A Tale of Two Markets for AIDS Vaccine (Developed vs. Developing World) - Dr. Don Francis (Vaxgen)
Date: 1/28/2004
Length: 5 minutes
Speaker(s): Dr. Don Francis
Sources: Stanford Technology Ventures Program
Description: The major market for the AIDS vaccine is in the developing world, says Francis, but there is significant demand in the United States with 40,000 new cases a year. There are a lot of unknowns in the business climate in the United
States affecting the profitability of a vaccine. It is difficult to encourage investment when a blockbuster drugs would have a much higher rate of return, he adds.

Other Videos in Series

A Tale of Two Markets for AIDS Vaccine (Developed vs. Developing World) - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: The major market for the AIDS vaccine is in the developing world, says Francis, but there is significant demand in the United States with 40,000 new cases a year. There are a lot of unknowns in the business climate in the United
States affecting the profitability of a vaccine. It is difficult to encourage investment when a blockbuster drugs would have a much higher rate of return, he adds. Watch More
Alliances and Collaboration - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Francis talks about how the NIH and the International AIDS Vaccine Initiative in New York are also doing AIDS vaccine research. With the help of his foundation, Gates envisions establishing a network of 6-10 AIDS vaccine
development centers that would be both competitive and collaborative in their mission to develop a vaccine. Watch More
Bush and 9/11 Put AIDS on the Back Burner - And a New Social Venture is Born - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Francis talks about how after 9/11, the government became interested in vaccines. Vaxgen shifted to making a small pox vaccine and an anthrax vaccine and has been very successful in these pursuits. Unfortunately, AIDS was not
named as an immediate concern and was but on the back burner. Due to the unwillingness of both the government and private businesses to provide funding, Francis has now decided that the AIDS vaccine cannot be developed in the private sector
and is founding a non-profit foundation to pursue the development of the vaccine for less developed parts of the world. Watch More
Career Advice: Follow Your Passion and Come to the Bay Area! - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Francis urges inspiring entrepreneurs to follow their passion. He comments on how difficult it is to follow a social cause in a society based on capitalism. The Bay Area is unique in its climate of venture capitalism and
risk-seizing attitude. Watch More
Don Francis's Mission - Kids and Kids' Health - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Don Francis, a pioneer in the field of HIV/AIDS research, had a long history as a pediatrician and an employee of the CDC before he joined Genentech to develop an AIDS vaccine. He realized that the only way to truly combat AIDS
was to develop a vaccine. He chose Genentech because it was the world leader on vaccines at that time, but he became disappointed when the development was not going anywhere and decided to start his own company. Watch More
Intellectual Property Issues Between Vaxgen and the New Social Venture - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Francis explains there are IP issues associated with forming the new venture, but since they are working for the less-developed world the licenses were given free of charge. Watch More
Is HIV Vaccine Possible? - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: The scary thing about HIV, says Francis, is the numerous variations around the world. Still, there is no scientific reason that it would not be possible to cover all the strains in a single vaccine; it would just be more expensive
to create such a vaccine, he adds. Watch More
Non-profit vs. Free Market: The Gates Foundation Changes the Game - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Neither private investors nor the government was willing to make the necessary investment in the vaccine, says Francis. Therefore, Francis and his team had to look elsewhere for funding. The formation of the Gates Foundation has
provided the desired alternative. Watch More
The Vaxgen Story - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Genentech and Vaxgen have spent a total of 20 years and $300 million on developing the vaccine, says Francis, but there is still a long way to go. Francis discusses some of the difficulties they have faced along the
way. Watch More
Vaccines Have a Social Problem! - Dr. Don Francis (Vaxgen)
Dr. Don Francis
1/28/2004
Summary: Francis talks about the social problem surrounding vaccines. People are only scared of a disease and willing to endure vaccination when they see evidence of the disease. Because vaccines are very effective at wiping out diseases,
he notes, society does not tend to be interested with vaccines. In general, society neglects preventative activities, but instead invests huge amounts of money when people actually do get sick, he adds. Watch More

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